DermaFix: Mandelic Acid (AHA) a Hero Ingredient Assisting in the Control of Anti-Ageing, Acne and Hyperpigmentation


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Mandelic Acid is a stabilised Alpha Hydroxy Acid (AHA), naturally derived from the hydrolysis of an extract obtained from bitter almonds.

In terms of molecular structure, the Mandelic acid molecule is larger than that of the widely used AHA, glycolic acid, and is therefore not as aggressive. This further means that there is less likelihood that ‘hotspots’ will develop with Mandelic acid as with other peeling agents.

The use of Mandelic acid within the skin care industry stems from its dual nature as an alpha hydroxy acid with potential cosmeceutical activity along with well-established antibacterial activity.

The earliest trial with Mandelic acid had two aims: to determine whether it can produce anti-ageing effects on the skin similar to those produced by glycolic acid, and to assess the antibacterial action of Mandelic acid in treating acne and preventing gram-negative bacterial infections after laser resurfacing.

Evaluation in the cosmeceutical industry over a period of 18 years has shown success in utilising Mandelic acid for the improvement of acne, skin texture, wrinkles, lentigenes and melasma. Results have been documented showing a significant improvement of hyperpigmentation when tested on the hands in a 28-day trial period. The skins texture improves with perceivable results within days of use, while fine lines and wrinkles showed improvement in photo-aged skin concerns and hyperpigmentation.

In 2006, the DermaFix Cosmeceutical Skin Care range was launched into the South African skin care market with the introduction of Mandelic Acid (AHA) as a ‘hero’ ingredient found within DermaFix DermaBright. Further Mandelic acid-based formulations have since been included within the DermaFix Cosmeceutical Skin Care range, and may be found in DermaFix MD Prescriptives Mandelic Cleanser and MD Prescriptives Mandelic Toner.

These above-mentioned products have the following skin care benefits:

  • MD Prescriptives Mandelic Cleanser is a mild, multifunctional cleanser that delicately yet deeply cleanses the skin. The skin re-acquires its original equilibrium dealing with various problematic skin care concerns.

  • MD Prescriptives Mandelic Toner is a 3-in-1 multi-purpose clarifying toner working to balance pH levels, assisting to control and reduce excess oil production for a clear and even complexion. It furthermore penetrates deep into pores to remove makeup and pore-clogging redundant skin cells while refining the surface of the skin.

  • DermaFix DermaBright ‘mini-peel’ is particularly useful in assisting to suppress hyperpigmentation, as well as working to treat inflammatory non-cystic acne while rejuvenating photo-aged skin. DermaFix DermaBright can be gradually incorporated into your evening skin care routine and may be added into any DermaFix cleansers as a wash, or may applied neat as advised by your DermaFix Skin Care Professional.

Get in touch with DermaFix South Africa

For more information on DermaFix products, or for further information relating to the DermaFix Cosmeceutical Skin Care brand, visit or call 0861 28 23 23.






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